Don't worry football fans, the month of May means its NFL schedule release time. The start of the season is less than four months away, but savvy bettors can take advantage early lines for marquee games. Thankfully, the league's announced a number of contests, including a Cowboys vs Eagles Week 1 showdown, as well as the entire international series slate.
I've scoured the early NFL schedule release odds to put together my best bets.
Cowboys vs Eagles Week 1 Odds
| Market | Cowboys | Eagles |
|---|---|---|
| Spread | +6.5 (-102) | -6.5 (-120) |
| Moneyline | +250 | -310 |
| Point Total | OVER 46.5 (-110) | UNDER 46.5 (-110) |
Buoyed by an outstanding off-season the Super Bowl champion Philadelphia Eagles enter the 2025 season with all the confidence in the world. The Eagles added Alabama linebacker Jihaad Campbell to their already outstanding front seven, re-signed NFL Defensive Player of the Year finalist Zack Baun, and picked up -rushers Ajeez Olajuri and Josh Uche.
Despite losing a ton of talent in free agency, Philadelphia is set to make a run at back-to-back championships. That run begins at home against their NFC East rival Cowboys. While Dallas made a splash by trading for George Pickens, the Cowboys draft haul was underwhelming and I fail to see how they keep up with the Eagles.
Bet on Jalen Hurts and company while you can still get the Eagles at under 6.5-point favorites.
Best bet: Eagles -6.5 (-120)
Vikings vs Steelers Week 4 Odds
| Market | Vikings | Steelers |
|---|---|---|
| Spread | -2.5 (-105) | +2.5 (-115) |
| Moneyline | -134 | +114 |
| Point Total | OVER 41.5 (-110) | UNDER 41.5 (-110) |
The NFL has released the international schedule for the 2025, and sportsbooks have followed along with odds for each contest.
Somehow, we've got early odds for Vikings vs Steelers in Dublin, Ireland. Despite neither team truly having their starting quarterback ready to play. After all, we've yet to hear about JJ McCarthy's recovery from meniscus surgery. On top of that, the only quarterbacks' currently on the Steelers roster are Mason Rudolph, Will Howard and Skyler Thompson. Now many have surmised that Pittsburgh has a long standing hand shake agreement in place with Aaron Rodgers to be their starter for the 2025 NFL season. However, at this point Rodgers is no sure thing.
Pittsburgh traded for DK Metcalf earlier in the off-season and later sent George Pickens to Dallas. On top of that, the Steelers added to their already strong defense by drafting Oregon defensive tackle Derrick Harmon in the first round and g Darius Slay in free agency.
There's a lot to unpack in this matchup, and still plenty to be decided upon on both depth charts, but I like the underdog Steelers to come out on top.
Best bet: Steelers ML (+114)
Broncos vs Jets Week 6 Odds
| Market | Broncos | Jets |
|---|---|---|
| Spread | -6.5 (-120) | +6.5 (-102) |
| Moneyline | -320 | +260 |
| Point Total | OVER 41.5 (-110) | UNDER 41.5 (-110) |
Bo Nix enters his sophomore season with great expectations for a Denver Broncos squad aiming to turn the corner. Sean Payton will have something special up his sleeve as the Broncos look to return to the postseason.
On the flip side, the Justin Fields-NYJ experiment will be in full flight by Week 6 when this game kicks off from Tottenham Hotspur Stadium, so we'll have a clear picture to base this bet on. At this point I like the Jets as underdogs. Sure the Broncos added some weapons in the draft, but I'm not ready to back Nix and the Broncos as full touchdown favorites against anyone just yet.
Best bet: Jets +6.5 (-102)
Rams vs Jaguars Week 7 Odds
| Market | Rams | Jaguars |
|---|---|---|
| Spread | -4.5 (-110) | +4.5 (-110) |
| Moneyline | -210 | +176 |
| Point Total | OVER 47.5 (-110) | UNDER 47.5 (-110) |
Can offensive mastermind Liam Coen fix Trevor Lawrence? That's the big question in Jacksonville. After the Jaguars traded up for weapon Travis Hunter in the NFL Draft, Lawrence is all out of excuses this season. Personally, I'm not ready to bet real currency on the Jags until I've seen Lawrence in action.
Plus, the Rams rabid and wildly productive defensive line has another year of experience, and Jacksonville's o-line leaves a lot to be desired. I'm backing the new-look Rams, as I think Puka Nacua and Davante Adams dominate this season.
Best bet: Rams -4.5 (-110)
Falcons vs Colts Week 10 Odds
| Market | Falcons | Colts |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-110) |
| Moneyline | -118 | +100 |
| Point Total | OVER 45.5 (-110) | UNDER 45.5 (-110) |
The fact of the matter is that each of the teams in this Week 10 Falcons vs Colts international series matchup could look drastically different by the time Week 10 rolls around. Will the Falcons hang on to Kirk Cousins in 2025? Could he take over as the starter if Michael Penix Jr. fails to impress?
Similarly, Colts fans will be clamoring for a leap in play from incumbent starter Anthony Richardson. But, Daniel Jones is lurking for what head coach Shane Steichen says is a wide open quarterback competition. With so many game linked factors up in the air, I'm rolling with the UNDER 45.5 as my best early bet for Falcons vs Colts from Olympic Stadium in Berlin, .
Best bet: UNDER 45.5 (-110)
Commanders vs Dolphins Week 11 Odds
| Market | Commanders | Dolphins |
|---|---|---|
| Spread | -2.5 (-115) | +2.5 (-105) |
| Moneyline | -146 | +124 |
| Point Total | OVER 49.5 (-110) | UNDER 49.5 (-110) |
Jayden Daniels and the Washington Commanders enter 2025 aiming to one up their NFC Championship game appearance. The NFL Offensive Rookie of the Year burst onto the scene in Washington, tossing for 3,568 yards and 25 touchdowns. Commanders vs Dolphins will be must-see TV as the action kicks off from the legendary Santiago Bernabeu Stadium in Madrid, Spain.
I'm backing Daniels to continue his strong run of play. Look for the reinforced Commanders defense to shut down the underwhelming Dolphins. This line will likely be greatly increased in Washington's favor once Week 11 rolls around, so get your Commanders vs Dolphins bets in now.
Best bet: Commanders -2.5 (-115)
